Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299108 | 0.85 | CA12 (0.39) | ALDH1A1MAPTNPSR1CA12CA1 | |
| SCHEMBL11324363 | 0.80 | MAPT (0.36) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL11299103 | 0.77 | NLRP3 (0.39) | ALDH1A1MAPTHPGDTDP1L3MBTL1 | |
| SCHEMBL31198124 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL31198087 | 0.76 | MMP8 (0.44) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL31198092 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL31198118 | 0.76 | MMP8 (0.44) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL11155678 | 0.75 | KMT2A (0.56) | ALDH1A1MAPTNPSR1CA12CA1 | |
| SCHEMBL31198051 | 0.74 | L3MBTL1 (0.52) | ALDH1A1MTNR1BTDP1L3MBTL1KDM4E | |
| SCHEMBL31198089 | 0.74 | MEN1 (0.44) | MAPTTDP1LMNAKDM4EMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |