Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472670 | 0.81 | SMN1; SMN2 (0.44) | NLRP3RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL11299108 | 0.78 | CA12 (0.39) | ALDH1A1LMNAHPGDNPC1RAB9A | |
| SCHEMBL11068682 | 0.77 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1LMNAKDM4EHPGD | |
| SCHEMBL11155853 | 0.77 | PTGER4 (0.42) | NLRP3L3MBTL1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL11324363 | 0.76 | MAPT (0.36) | ALDH1A1L3MBTL1LMNAKDM4EHPGD | |
| SCHEMBL31198070 | 0.74 | TDP1 (0.44) | NLRP3ALDH1A1TDP1NPC1MAPK1 | |
| SCHEMBL11155682 | 0.74 | TSHR (0.57) | ALDH1A1L3MBTL1LMNAKDM4EHPGD | |
| SCHEMBL31198075 | 0.73 | PIN1 (0.46) | NLRP3ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL11071275 | 0.72 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1LMNAKDM4EHPGD | |
| SCHEMBL31198091 | 0.72 | PIN1 (0.41) | NLRP3ALDH1A1KDM4ETDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |