Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071289 | 0.83 | KDM4E (0.45) | HPGDALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11061402 | 0.81 | ALDH1A1 (0.36) | HPGDALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11068912 | 0.76 | METAP2 (0.45) | HPGDALDH1A1 | |
| SCHEMBL11064529 | 0.72 | ALDH1A1 (0.43) | HPGDALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11073590 | 0.70 | ALDH1A1 (0.37) | HPGDALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11070577 | 0.69 | GAA (0.41) | HPGDALDH1A1MAPTGAAKDM4E | |
| SCHEMBL17938280 | 0.68 | ALDH1A1 (0.68) | HPGDALDH1A1MAPTGAAKDM4E | |
| SCHEMBL8962350 | 0.66 | HPGD (0.54) | HSD17B3HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL26254861 | 0.66 | HSD17B3 (0.82) | HSD17B3HPGDALDH1A1GAAKDM4E | |
| SCHEMBL26958041 | 0.65 | HSD17B3 (0.61) | HSD17B3HPGDALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476132-A | Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |