Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071842 | 0.86 | SLC18A3 (0.48) | CHRNA7HTR7LMNAGAAPKM | |
| SCHEMBL11069003 | 0.85 | DRD4 (0.62) | GAAMEN1KMT2ADRD4DRD2 | |
| SCHEMBL10571746 | 0.83 | HTR7 (0.66) | HTR7LMNAKMT2ANPSR1KDM4E | |
| SCHEMBL11071345 | 0.77 | — | — | |
| SCHEMBL11068145 | 0.74 | KCNH2 (0.49) | — | |
| SCHEMBL11066226 | 0.74 | DRD4 (0.62) | GAAMEN1KMT2ADRD4 | |
| SCHEMBL10568734 | 0.74 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL10568883 | 0.74 | HTR7 (0.51) | HTR7LMNAKMT2ADRD4DRD2 | |
| SCHEMBL11072463 | 0.73 | DRD2 (0.46) | CHRNA7HTR7LMNAGAAPKM | |
| SCHEMBL11064740 | 0.73 | PRMT5 (0.47) | CHRNA7HTR7LMNAGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |