Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064570 | 0.88 | TRPM8 (0.43) | MAPK1HSD17B10NPC1LMNAALOX15 | |
| SCHEMBL11065939 | 0.87 | TRPM8 (0.44) | MAPK1HSD17B10NPC1LMNAALOX15 | |
| SCHEMBL11319811 | 0.84 | PDE3B (0.49) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL11068361 | 0.83 | DRD2 (0.45) | DRD2DRD4DRD3ADRB2ADRB1 | |
| SCHEMBL11067557 | 0.82 | ADRB2 (0.39) | MAPK1HSD17B10NPC1LMNAALOX15 | |
| SCHEMBL11062524 | 0.81 | ADRB2 (0.41) | MAPK1HSD17B10NPC1LMNAALOX15 | |
| SCHEMBL11069685 | 0.81 | ADRB2 (0.41) | MAPK1HSD17B10NPC1LMNAALOX15 | |
| SCHEMBL11065776 | 0.81 | ADRB2 (0.40) | MAPK1HSD17B10NPC1LMNAALOX15 | |
| SCHEMBL11062582 | 0.80 | ADRB2 (0.40) | MAPK1HSD17B10NPC1LMNAALOX15 | |
| SCHEMBL11319220 | 0.80 | ADRB1 (0.51) | TSHRDRD2DRD4DRD3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313947-A | TREATMENT OF BLOOD DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4216220-A | Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-05 | — | — | US | disclosed |
| US-4070470-A | BENCYCLOAMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |