Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092177 | 0.79 | ALDH1A1 (0.53) | POLBALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL11069887 | 0.76 | ALDH1A1 (0.44) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL15670616 | 0.75 | KMT2A (0.49) | POLBALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL2564116 | 0.73 | APLNR (0.50) | ALDH1A1TSHRKMT2AMEN1HTT | |
| SCHEMBL13544517 | 0.70 | TAS1R3 (0.53) | POLBALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL2564118 | 0.70 | POLB (0.52) | POLBALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL10903904 | 0.70 | ALDH1A1 (0.44) | POLBALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL15366455 | 0.69 | ALDH1A1 (0.47) | POLBALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL11160909 | 0.67 | HSD17B10 (0.55) | KMT2AMEN1 | |
| SCHEMBL21246777 | 0.67 | TSPO (0.49) | POLBALDH1A1KDM4ETSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435322-A | Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-03-06 | — | — | US | disclosed |