Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | RNF4 | P78317 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16989819 | 0.79 | RIPK1 (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11070387 | 0.76 | POLB (0.43) | ALDH1A1HTTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL20424234 | 0.75 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9AHTTPAX8 | |
| SCHEMBL11070058 | 0.73 | ALOX5 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL20424232 | 0.70 | NPC1 (0.49) | ALDH1A1NPC1RAB9AHTTPAX8 | |
| SCHEMBL5603445 | 0.69 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL23803543 | 0.69 | RIPK1 (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6770925 | 0.69 | CNR2 (0.35) | RIPK1 | |
| SCHEMBL2931129 | 0.67 | ALDH1A1 (0.66) | ALDH1A1NPC1RAB9AHTTPAX8 | |
| SCHEMBL17460412 | 0.67 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435322-A | Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-03-06 | — | — | US | disclosed |