Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.50 |
| ▸ | DRD4 | P21917 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066548 | 0.89 | DRD4 (0.60) | HRH3CHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL11063081 | 0.88 | DRD4 (0.59) | HRH3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11062798 | 0.83 | CHRM2 (0.60) | HRH3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11066898 | 0.82 | DRD2 (0.53) | HRH3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11063325 | 0.80 | CHRM2 (0.53) | HRH3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10570155 | 0.78 | HTR1A (0.57) | HRH3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11064799 | 0.77 | TMEM97 (0.53) | HRH3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11063504 | 0.76 | KCNH2 (0.50) | HRH3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11072709 | 0.75 | MEN1 (0.47) | HRH3DRD2DRD3MEN1KMT2A | |
| SCHEMBL11067274 | 0.75 | ABCB1 (0.48) | DRD4DRD2MEN1KMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |