Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073298 | 0.85 | ABCB1 (0.61) | MEN1KMT2AALDH1A1LMNAABCB1 | |
| SCHEMBL11065111 | 0.84 | SIGMAR1 (0.53) | SIGMAR1DRD2HTR7HTR1ADRD1 | |
| SCHEMBL11070828 | 0.82 | OPRL1 (0.47) | SIGMAR1OPRL1 | |
| SCHEMBL10570155 | 0.81 | HTR1A (0.57) | SIGMAR1DRD2HRH3HTR1AHTR2A | |
| SCHEMBL11071740 | 0.81 | HTR7 (0.50) | MEN1KMT2AALDH1A1LMNASIGMAR1 | |
| SCHEMBL11066898 | 0.80 | DRD2 (0.53) | MEN1KMT2ASIGMAR1DRD2HRH3 | |
| SCHEMBL11070967 | 0.78 | DRD2 (0.53) | MEN1KMT2AALDH1A1LMNASIGMAR1 | |
| SCHEMBL11066548 | 0.78 | DRD4 (0.60) | MEN1KMT2AALDH1A1SIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL11063081 | 0.77 | DRD4 (0.59) | MEN1KMT2AALDH1A1SIGMAR1DRD2 | |
| SCHEMBL10572119 | 0.76 | HTR1A (0.57) | SIGMAR1DRD2HRH3HTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |