Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628544 | 0.95 | CYP3A4 (0.67) | CYP3A4TSHRCYP1A2SAE1UBA2 | |
| SCHEMBL13907414 | 0.89 | TSHR (0.57) | CYP3A4TSHRCYP1A2LOXL2CYP2A6 | |
| SCHEMBL135741 | 0.88 | CYP3A4 (0.52) | CYP3A4TSHRCYP1A2LOXL2CYP2A6 | |
| Water SCHEMBL8522858 | 0.88 | CYP3A4 (0.95) | CYP3A4TSHRCYP1A2SAE1UBA2 | |
| SCHEMBL12446977 | 0.87 | CYP3A4 (0.56) | CYP3A4TSHRCYP1A2SAE1UBA2 | |
| SCHEMBL19943 | 0.86 | CYP3A4 (1.00) | CYP3A4TSHRCYP1A2HTTMAPK1 | |
| SCHEMBL12852256 | 0.86 | CYP3A4 (1.00) | CYP3A4TSHRCYP1A2HTTMAPK1 | |
| SCHEMBL1396496 | 0.86 | CYP3A4 (1.00) | CYP3A4TSHRCYP1A2HTTMAPK1 | |
| SCHEMBL2044965 | 0.86 | CYP3A4 (1.00) | CYP3A4TSHRCYP1A2HTTMAPK1 | |
| SCHEMBL30634516 | 0.84 | CYP3A4 (0.95) | CYP3A4TSHRCYP1A2HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017016755-A1 | ORGANIC AEROGELS BASED ON ISOCYANATE AND CYCLIC ETHER POLYMER NETWORKS | HENKEL AG & CO. KGAA (DE) | 2017-02-02 | — | — | WO | disclosed |
| US-8329850-B2 | Golf equipment formed from castable formulation with unconventionally low hardness and increased shear resistance | ACUSHNET COMPANY (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120296003-A1 | DENTAL MATERIAL, DENTAL MATERIAL COMPOSITION, DENTAL RESTORATIVE MATERIAL, AND CURED PRODUCT | MITSUI CHEMICALS, INC (JP) | 2012-11-22 | — | — | US | disclosed |
| US-20120289619-A1 | Flame Retardant Polyurethane Foams Containing Biuret Linkages | DOW GLOBAL TECHNOLOGIES LLC. | 2012-11-15 | — | — | US | disclosed |
| US-8257913-B2 | Processing method of lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2012-09-04 | — | — | US | disclosed |
| US-8151705-B2 | Method of preparing lithographic printing plate | FUJIFILM CORPORATION (JP) | 2012-04-10 | — | — | US | disclosed |
| US-8119326-B2 | Lithographic-printing plate precursor and image forming method using the same | EASTMAN KODAK COMPANY (US) | 2012-02-21 | — | — | US | disclosed |
| US-7994269-B2 | Golf equipment formed from castable formulation with unconventionally low hardness and increased shear resistance | ACUSHNET COMPANY (US) | 2011-08-09 | — | — | US | disclosed |
| US-7985535-B2 | Image-forming method and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2011-07-26 | — | — | US | disclosed |
| US-20110105636-A1 | ORGANIC AEROGEL, COMPOSITION FOR THE MANUFACTURE OF THE ORGANIC AEROGEL, AND METHOD OF MANUFACTURING THE ORGANIC AEROGEL | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-05-05 | — | — | US | disclosed |
| US-20090053653-A1 | POLYMERIZABLE COMPOSITION AND LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2009-02-26 | — | — | US | disclosed |
| US-7491487-B2 | Polymerizable composition and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2009-02-17 | — | — | US | disclosed |
| US-7449282-B2 | Lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20080268372-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2008-10-30 | — | — | US | disclosed |
| US-20080261153-A1 | PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |
| US-20080194881-A1 | Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives | SOLVAY SOLEXIS S.P.A. (IT) | 2008-08-14 | — | — | US | disclosed |
| US-20080161214-A1 | Urea-Based Lubricating Grease Composition | SHELL OIL COMPANY (US) | 2008-07-03 | — | — | US | disclosed |
| US-20080071021-A1 | FLUOROACRYLATE-MERCAPTOFUNCTIONAL COPOLYMERS | 3M INNOVATIVE PROPERTIES COMPANY | 2008-03-20 | — | — | US | disclosed |
| US-20080057437-A1 | heat-decomposable cured polyurethane having an aromatic group is directly connected to a urethane bond; high sensitivity to easily form a pattern | FUJIFILM CORPORATION (JP) | 2008-03-06 | — | — | US | disclosed |
| WO-2007126410-A2 | HYBRID ORGANIC-INORGANIC MATERIALS AND METHODS OF PREPARING THE SAME | ASPEN AEROGELS INC. (US) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194881-A1 | Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives | FOXO1, FOXM1, F12 | CYP3A4 3727/4885TSHR 1254/4885CYP1A2 2818/4885 |
| US-20120296003-A1 | DENTAL MATERIAL, DENTAL MATERIAL COMPOSITION, DENTAL RESTORATIVE MATERIAL, AND CURED PRODUCT | CAD, SEM1, REV1 | CYP3A4 4021/4885TSHR 4854/4885CYP1A2 2796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.