Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.62 |
| ▸ | SCN1A | P35498 | 2/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072939 | 0.89 | DRD4 (0.62) | DRD4SCN1ASCN5ASCN9AABCB1 | |
| SCHEMBL11066967 | 0.87 | SCN1A (0.55) | DRD4SCN1ASCN5ASCN9AADRB2 | |
| SCHEMBL11070939 | 0.85 | MAOA (0.52) | DRD4SCN1ASCN5ASCN9AMAOA | |
| SCHEMBL11073307 | 0.84 | MAOA (0.57) | DRD4DRD2MAOAMAOBADRB1 | |
| SCHEMBL11065044 | 0.83 | MAOA (0.61) | DRD4DRD2MAOAMAOBADRB2 | |
| SCHEMBL10572684 | 0.83 | SCN5A (0.54) | SCN1ASCN5ASCN9ADRD2ADRB2 | |
| Hydrochloric Acid SCHEMBL11067443 | 0.82 | MAOA (0.60) | DRD4MAOAMAOBKMT2AMEN1 | |
| SCHEMBL11065083 | 0.82 | MAOA (0.65) | DRD4MAOAMAOBKMT2AMEN1 | |
| SCHEMBL11067861 | 0.81 | DRD4 (0.62) | DRD4ABCB1DRD2ADRB2ADRB1 | |
| SCHEMBL11071590 | 0.81 | MAOA (0.69) | DRD4DRD2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |