Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063139 | 0.92 | DRD3 (0.47) | HTR7DRD2DRD3DRD4KCNA3 | |
| SCHEMBL11068976 | 0.88 | S1PR5 (0.47) | HTR7DRD2DRD3DRD4KCNA3 | |
| SCHEMBL11066899 | 0.86 | HTR7 (0.50) | HTR7DRD2DRD3DRD4 | |
| SCHEMBL11067562 | 0.85 | HTR7 (0.53) | HTR7DRD2DRD3DRD4GAA | |
| SCHEMBL11070408 | 0.84 | CCR1 (0.57) | HTR7GAA | |
| SCHEMBL11064993 | 0.83 | HTR7 (0.51) | HTR7DRD2DRD3DRD4GAA | |
| SCHEMBL11062767 | 0.80 | MAOA (0.66) | DRD2DRD3DRD4 | |
| SCHEMBL11070987 | 0.80 | DRD2 (0.60) | HTR7DRD2DRD3DRD4 | |
| SCHEMBL10569528 | 0.80 | KCNA5 (0.50) | DRD2DRD3DRD4 | |
| SCHEMBL11071121 | 0.79 | DRD2 (0.53) | HTR7DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |