Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | TACR3 | P29371 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071804 | 0.83 | HTR7 (0.53) | HTR7GAAKCNA3MAPTDRD2 | |
| SCHEMBL11064059 | 0.80 | HRH3 (0.46) | HTR7TACR2TACR1TACR3HRH3 | |
| SCHEMBL11067562 | 0.77 | HTR7 (0.53) | HTR7GAAKCNA3MAPTDRD2 | |
| SCHEMBL11066798 | 0.76 | HTR7 (0.42) | HTR7TACR2TACR1TACR3HRH3 | |
| SCHEMBL11063730 | 0.76 | TACR2 (0.43) | HTR7TACR2TACR1TACR3HRH3 | |
| SCHEMBL11063139 | 0.75 | DRD3 (0.47) | HTR7KCNA3DRD2DRD4DRD3 | |
| SCHEMBL11071377 | 0.73 | — | — | |
| SCHEMBL11060233 | 0.73 | CHRM1 (0.50) | DRD2DRD4DRD3 | |
| SCHEMBL11065503 | 0.73 | OPRM1 (0.53) | HTR7TACR2TACR1TACR3GAA | |
| SCHEMBL27651992 | 0.73 | GAA (0.52) | HTR7TACR2TACR1TACR3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |