Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066636 | 0.83 | TDP1 (0.55) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL4876593 | 0.77 | TDP1 (0.60) | MAPK1TDP1ALDH1A1HTTVCAM1 | |
| SCHEMBL989963 | 0.73 | MAPT (0.60) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL27893370 | 0.72 | LMNA (0.52) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11015444 | 0.72 | TDP1 (0.53) | MAPTTDP1HTTVCAM1MEN1 | |
| SCHEMBL14940799 | 0.72 | MAPT (0.62) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9388637 | 0.71 | TDP1 (0.44) | MAPTMAPK1TDP1ALDH1A1HTT | |
| SCHEMBL9301608 | 0.70 | TDP1 (0.40) | MAPTMAPK1TDP1ALDH1A1HTT | |
| SCHEMBL30814308 | 0.69 | ALDH1A1 (0.38) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL278488 | 0.68 | TDP1 (1.00) | MAPK1TDP1ALDH1A1VCAM1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31717-E | 2-Chloro-3-(phenoxy or phenylthio)-6-nitro-anilines | CELAMERCK GMBH & CO. KG (DE) | 1984-10-30 | — | — | US | disclosed |
| US-4394159-A | HERBICIDES | CELAMERCK GMBH & CO. KG (DE) | 1983-07-19 | — | — | US | disclosed |
| EP-0007482-A1 | 2-Chloro-6-nitroanilines, process for their preparation, their use, herbicidal compositions | CELAMERCK GmbH & Co. KG (DE) | 1980-02-06 | — | — | EP | disclosed |