Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1099249 | 0.98 | ALOX5 (0.47) | ALOX5ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL2177279 | 0.79 | CYP2A6 (0.52) | ALOX5ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL28017683 | 0.78 | ALOX5 (0.43) | ALOX5ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL1479681 | 0.77 | ALOX5 (0.42) | ALOX5ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL16023610 | 0.75 | ALOX5 (0.41) | ALOX5ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL105045 | 0.75 | NR4A2 (0.42) | ALOX5ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL306185 | 0.75 | HTT (0.42) | ALOX5ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL8113780 | 0.75 | ALOX5 (0.41) | ALOX5ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL3483357 | 0.75 | ALOX5 (0.44) | ALOX5ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL31001832 | 0.75 | NR4A2 (0.42) | ALOX5ALDH1A1MAPTKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1910190-A | Thienopyrimidine and thienopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO LTD (JP) | 2007-02-07 | — | — | CN | claimed |
| WO-2004082686-A2 | USE OF COMPOUNDS WITH COMBINED 5-HT1A AND SSRI ACTIVITIES TO TREAT SEXUAL DYSFUNCTION | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | WO | claimed |
| US-20040192730-A1 | Methods of using compounds with combined 5-HT1A and SSRI activities as-needed to treat sexual dysfunction | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | US | claimed |
| JP-6179681-A | — | — | None | — | — | JP | disclosed |
| CN-117486794-A | Polysubstituted quinoline derivative and synthetic method and application thereof | 华东师范大学 | 2024-02-02 | — | — | CN | disclosed |
| US-10198478-B2 | Methods and systems for technology analysis and mapping | MAGIC NUMBER, INC. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20170046398-A1 | Methods and systems for technology analysis and mapping | SPORE, INC. (US) | 2017-02-16 | — | — | US | disclosed |
| US-9483551-B2 | Methods and systems for technology analysis and mapping | SPORE, INC. (US) | 2016-11-01 | — | — | US | disclosed |
| US-9434711-B2 | Sulfonamides as TRPM8 modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2016-09-06 | — | — | US | disclosed |
| US-9434711-B2 | Sulfonamides as TRPM8 modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2016-09-06 | — | — | US | disclosed |
| CN-101591346-B | Novel method for synthesizing related substance B of clopidogrel bisulfate | BEIJING HUAXI PHARM. CO., LTD. (CN) | 2014-10-29 | — | — | CN | disclosed |
| EP-0581106-B1 | Substituted aminothienopyridines, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0581106-B1 | Substituted aminothienopyridines, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-05-20 | — | — | EP | disclosed |
| US-5519032-A | ANTIDEPRESSANTS, ANXIOLYTICS, ANTIEMETICS, ANTIPSYCHOTIC | HOECHST MARION ROUSSEL INC. (US) | 1996-05-21 | — | — | US | disclosed |
| US-5519032-A | ANTIDEPRESSANTS, ANXIOLYTICS, ANTIEMETICS, ANTIPSYCHOTIC | HOECHST MARION ROUSSEL INC. (US) | 1996-05-21 | — | — | US | disclosed |
| JP-H06179681-A | SUBSTITUTED AMINOTHIENOPYRIDINES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | HOECHST ROUSSEL PHARMACEUT INC | 1994-06-28 | — | — | JP | disclosed |
| EP-0581106-A1 | Substituted aminothienopyridines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-02-02 | — | — | EP | disclosed |
| EP-0581106-A1 | Substituted aminothienopyridines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5252581-A | Modulators of neurotransmitters | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-10-12 | — | — | US | disclosed |
| US-5252581-A | Modulators of neurotransmitters | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192730-A1 | Methods of using compounds with combined 5-HT1A and SSRI activities as-needed to treat sexual dysfunction | HTR5A, HTR1A, HTR3A | ALOX5 137/4885ALDH1A1 529/4885MAPT 3682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.