SCHEMBL11073038

SCHEMBL11073038

CC=Cc1ccc(Cl)c(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHAT P28329 1/20 0.55
ALDH1A1 P00352 2/20 0.54
CNR2 P34972 1/20 0.48
PYGL P06737 7/20 0.46
SLC6A3 Q01959 1/20 0.44
KDM4A O75164 1/20 0.44
KDM4B O94953 1/20 0.44
CYP3A4 P08684 2/20 0.44
ATM Q13315 1/20 0.44
PTGS2 P35354 1/20 0.44
TYR P14679 1/20 0.42
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NPFFR2 Q9Y5X5 1/20 0.41
GUSB P08236 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11438887 1.00 CHAT (0.55) CHATALDH1A1CNR2PYGLSLC6A3
SCHEMBL265106 1.00 CHAT (0.55) CHATALDH1A1CNR2PYGLSLC6A3
SCHEMBL10973260 0.85 ALDH1A1 (0.64) CHATALDH1A1PYGLKDM4AKDM4B
SCHEMBL10973255 0.85 ALDH1A1 (0.64) CHATALDH1A1PYGLKDM4AKDM4B
SCHEMBL7807626 0.85 CHAT (0.50) CHATALDH1A1CNR2PYGLSLC6A3
SCHEMBL7807620 0.85 CHAT (0.50) CHATALDH1A1CNR2PYGLSLC6A3
SCHEMBL9720849 0.82 CHAT (0.67) CHATALDH1A1PYGLKDM4AKDM4B
SCHEMBL9720852 0.82 CHAT (0.67) CHATALDH1A1PYGLKDM4AKDM4B
SCHEMBL22548434 0.82 CNR2 (0.45) CHATALDH1A1CNR2CYP3A4ATM
SCHEMBL13888715 0.80 CNR2 (0.59) ALDH1A1CNR2CYP3A4ATMPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423433-B1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO PHARM SOLUTIONS CO LTD (KR) 2025-12-17 EP disclosed
CN-109071424-B Sulfamate derivative compound, preparation method and application thereof 生物药品解决方案有限公司 2022-01-14 CN disclosed
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses BIO-PHARM SOLUTIONS CO., LTD. (KR) 2019-07-16 US disclosed
EP-3423433-A1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES Bio-Pharm Solutions Co., Ltd. (KR) 2019-01-09 EP disclosed
US-4467066-A DIENE-VINYLARENE STAR POLYMER, POLYDIENE, VINYLARENE BLENDS SHELL OIL COMPANY (US) 1984-08-21 US disclosed
EP-0018144-A1 A process for the preparation of substituted 2-aminopyrazines ELI LILLY AND COMPANY (US) 1980-10-29 EP disclosed
EP-0017494-A2 Hydroxyimino-substituted aminoacetonitrile intermediates and their preparation ELI LILLY AND COMPANY (US) 1980-10-15 EP disclosed
US-4211870-A FROM AMINOACETONITRILE AND A PHENYL A-HALO OXIME ELI LILLY AND COMPANY (US) 1980-07-08 US disclosed
US-4199525-A Hydroxyimino-substituted aminoacetonitriles ELI LILLY AND COMPANY (US) 1980-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses STS, SULT2A1, SULT1A1 CHAT 706/4885ALDH1A1 844/4885CNR2 401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.