SCHEMBL11079388

SCHEMBL11079388

COC(=O)C1(CCCOCCCCCCC2CCCC2)CO1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.41
NAAA Q02083 11/20 0.40
FKBP1A P62942 1/20 0.38
GPR119 Q8TDV5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11068141 0.93 FKBP1A (0.39) EPHX1NAAAFKBP1A
SCHEMBL11079057 0.92 EPHX1 (0.44) EPHX1NAAAFKBP1A
SCHEMBL11070610 0.92 EPHX1 (0.44) EPHX1NAAAFKBP1A
SCHEMBL11073121 0.92 ABCB11 (0.40) EPHX1NAAAGPR119
SCHEMBL11075218 0.92 SIGMAR1 (0.39) EPHX1NAAA
SCHEMBL11077158 0.92 SIGMAR1 (0.39) EPHX1NAAA
SCHEMBL11068963 0.92 SIGMAR1 (0.39) EPHX1NAAA
SCHEMBL11074335 0.91 ABCB11 (0.38) EPHX1NAAAFKBP1A
SCHEMBL11070035 0.91 NAAA (0.36) EPHX1NAAAFKBP1A
SCHEMBL11072205 0.91 NAAA (0.36) EPHX1NAAAFKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4430339-A PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-02-07 US disclosed