Metacresol

Metacresol

SCHEMBL11073151

C=CCc1cccc(O)c1.Cc1cccc(O)c1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.59
OPRM1 P35372 4/20 0.47
OPRD1 P41143 4/20 0.47
OPRK1 P41145 4/20 0.47
XDH P47989 1/20 0.46
ALDH1A1 P00352 2/20 0.44
GAA P10253 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
ALDH2 P05091 1/20 0.44
MAPT P10636 1/20 0.44
GABRA1 P14867 1/20 0.44
AKR1B1 P15121 1/20 0.44
HPGD P15428 1/20 0.44
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
PPARG P37231 1/20 0.44
GABRB2 P47870 1/20 0.44
KMT2A Q03164 1/20 0.44
PPARD Q03181 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30001086 0.89 OPRM1 (0.56) ACHEOPRM1OPRD1OPRK1XDH
SCHEMBL299759 0.89 OPRM1 (0.56) ACHEOPRM1OPRD1OPRK1XDH
Phenol SCHEMBL28307830 0.88 ACHE (0.47) ACHEOPRM1OPRD1OPRK1XDH
SCHEMBL2137377 0.85 TAAR1 (0.50) ACHEXDHALDH1A1GAAKDM4E
SCHEMBL31481296 0.85 TAAR1 (0.50) ACHEXDHALDH1A1GAAKDM4E
SCHEMBL28988330 0.85 ALDH1A1 (0.47) ACHEOPRM1OPRD1OPRK1XDH
Phenol SCHEMBL5932073 0.84 OPRK1 (0.51) OPRM1OPRD1OPRK1XDHALDH1A1
Acetic Acid SCHEMBL11403510 0.83 PTGS2 (0.50) OPRM1OPRD1OPRK1XDHALDH1A1
Metacresol SCHEMBL10761467 0.79 ACHE (0.77) ACHEALDH1A1CYP1A2CYP2C19CYP3A4
Metacresol SCHEMBL11209132 0.79 ACHE (0.53) ACHEOPRM1OPRD1OPRK1XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0012613-B1 A PROCESS FOR PRODUCING 3-ALKYLPHENOLS AND 1,3-DIHYDROXYBENZENE MOBIL OIL CORPORATION (US) 1984-08-08 EP claimed