SCHEMBL11074191

SCHEMBL11074191

Cc1ccc2ccccc2[n+]1C.O=S(=O)([O-])c1ccc(Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.45
ALDH1A1 P00352 4/20 0.44
GAA P10253 2/20 0.44
KDM4E B2RXH2 2/20 0.44
HPGD P15428 1/20 0.44
POLB P06746 2/20 0.38
PTGS2 P35354 1/20 0.36
ALDH3A1 P30838 1/20 0.35
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
NPSR1 Q6W5P4 1/20 0.34
FLT1 P17948 1/20 0.33
FLT4 P35916 1/20 0.33
KDR P35968 1/20 0.33
KAT6A Q92794 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1001565 0.88 KDM4E (0.46) ALDH1A1GAAKDM4EHPGDPOLB
SCHEMBL15879007 0.84 ALDH1A1 (0.45) ALDH1A1GAAKDM4EHPGDMAPK1
SCHEMBL15879541 0.83 PKM (0.47) ACHEALDH1A1GAAKDM4EHPGD
SCHEMBL11799281 0.81 TERT (0.37) ACHEKDM4EHPGDPOLBKMT2A
SCHEMBL382590 0.79 KDM4E (0.48) ACHEALDH1A1GAAKDM4EHPGD
Trifluoromethanesulfonic Acid SCHEMBL4881196 0.78 KDM4E (0.47) ACHEALDH1A1GAAKDM4EHPGD
SCHEMBL30929898 0.78 ACHE (0.47) ACHEALDH1A1GAAKDM4EHPGD
SCHEMBL1044982 0.78 ACHE (0.47) ACHEALDH1A1GAAKDM4EHPGD
SCHEMBL11063962 0.76 KDM4E (0.43) ALDH1A1GAAKDM4EHPGDPOLB
Iodide SCHEMBL2031115 0.76 ACHE (0.50) ACHEALDH1A1GAAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4431774-A QUINOLINIUM SULFONATES AS LATENT ACID CATALYSTS; RADIATION; DECOMPOSITION; STORAGE STABILITY CIBA-GEIGY CORPORATION (US) 1984-02-14 US disclosed