Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.76 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beclobrate SCHEMBL49779 | 0.87 | OPRK1 (1.00) | OPRK1PPARAABCB11CYP1A2CYP3A4 | |
| Beclobrate SCHEMBL3950803 | 0.87 | OPRK1 (1.00) | OPRK1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL1935420 | 0.83 | OPRK1 (0.86) | OPRK1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11288479 | 0.79 | OPRK1 (0.68) | OPRK1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL5997445 | 0.78 | OPRK1 (0.78) | OPRK1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11071767 | 0.77 | OPRK1 (0.81) | OPRK1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11063131 | 0.77 | OPRK1 (0.81) | OPRK1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11070815 | 0.76 | OPRK1 (0.79) | OPRK1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11470655 | 0.76 | OPRK1 (0.79) | OPRK1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11072228 | 0.75 | OPRK1 (0.78) | OPRK1PPARAABCB11CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483999-A | Phenoxy alkanoic acid derivatives having the ability to lower the level of fatty substances in the blood | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1984-11-20 | — | — | US | disclosed |