Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295878 | 0.83 | OPRM1 (0.43) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL10887416 | 0.82 | RXRA (0.39) | CYP3A4 | |
| SCHEMBL11077426 | 0.82 | MEN1 (0.42) | SMN1; SMN2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL12737809 | 0.77 | ALDH1A1 (0.42) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL10885974 | 0.76 | NOTUM (0.42) | SMN1; SMN2CYP3A4CYP2D6CYP2C19LMNA | |
| SCHEMBL14992935 | 0.75 | POLB (0.41) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL8901599 | 0.75 | GAA (0.47) | KCNH2TSHRLMNA | |
| SCHEMBL9364772 | 0.73 | BRD4 (0.59) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL12919612 | 0.72 | ATM (0.46) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL12919619 | 0.71 | OPRM1 (0.43) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481133-A | NATHTALENE AND INDANE NITRILES | GIVAUDAN CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |
| US-4406828-A | ACETYL AND PROPIONYL INDANES AND TETRALINS | GIVAUDAN CORPORATION (US) | 1983-09-27 | — | — | US | disclosed |