Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077433 | 0.82 | LMNA (0.44) | LMNAUTS2RSLC6A4HTR1AHTR1B | |
| SCHEMBL11076554 | 0.81 | AKT1 (0.50) | LMNAHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL11074440 | 0.78 | AKT1 (0.46) | LMNAUTS2RSLC6A4HTR7KCNH2 | |
| SCHEMBL11075163 | 0.69 | AKT1 (0.46) | DRD2DRD3 | |
| SCHEMBL27456056 | 0.67 | HTR1A (0.39) | HTR1AHTR1BHTR2AHTR2CHTR7 | |
| SCHEMBL9749197 | 0.66 | SSTR5 (0.37) | LMNAHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL11244215 | 0.64 | AKT1 (0.50) | LMNAHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL11078511 | 0.63 | POLB (0.41) | LMNAMAPT | |
| SCHEMBL11075158 | 0.62 | DRD2 (0.34) | HTR1ADRD2DRD3 | |
| SCHEMBL11075660 | 0.62 | HTR2A (0.40) | LMNAHTR2AHTR2CDRD2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452801-A | ANTIINFLAMMATORY AGENTS, ANTICOAGULATNS, ANTIALLERGENS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4360532-A | ANTIINFLAMMATORY AGENTS, ANTICOAGULANTS, ANTIALLERGENS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-11-23 | — | — | US | disclosed |
| US-4321270-A | ANTIINFLAMMATORY AGENT, ANTIAGGLOMERANTS, AND HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-03-23 | — | — | US | disclosed |