Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2351646 | 0.83 | THRB (0.40) | THRBAKR1B1CA2CXCL8THRA | |
| SCHEMBL4837065 | 0.83 | AKR1B1 (0.45) | AKR1B1CA2CXCL8CAMK2ACYP2C9 | |
| SCHEMBL27754268 | 0.82 | F11 (0.36) | THRBAKR1B1CA2CXCL8THRA | |
| SCHEMBL29159998 | 0.79 | KDM1A (0.40) | THRBAKR1B1CA2CXCL8THRA | |
| SCHEMBL30028576 | 0.79 | THRB (0.40) | THRBAKR1B1CA2CXCL8THRA | |
| SCHEMBL22701184 | 0.79 | THRB (0.37) | THRBAKR1B1CA2CXCL8THRA | |
| SCHEMBL3606718 | 0.79 | THRB (0.44) | THRBCXCL8THRAPTGS2 | |
| SCHEMBL17847027 | 0.79 | THRB (0.40) | THRBAKR1B1CA2CXCL8THRA | |
| SCHEMBL5011997 | 0.78 | AKR1B1 (0.44) | THRBAKR1B1THRAMEN1KMT2A | |
| SCHEMBL31570157 | 0.78 | CYP1A2 (0.53) | AKR1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144059-A2 | Photographic element | FUJI PHOTO FILM CO., LTD. (JP) | 1985-06-12 | — | — | EP | disclosed |
| US-4426536-A | Synthesis of phenylacetic acid esters | ELI LILLY AND COMPANY (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0098058-A1 | Synthesis of phenylacetic acid esters | ELI LILLY AND COMPANY (US) | 1984-01-11 | — | — | EP | disclosed |