Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372041 | 0.82 | FAAH (0.64) | FAAHNAAAHSD17B10NPSR1SMN1; SMN2 | |
| SCHEMBL8718626 | 0.81 | FAAH (0.39) | FAAHNAAAHSD17B10NPSR1GAA | |
| SCHEMBL4971017 | 0.81 | FAAH (0.39) | FAAHNAAAHSD17B10NPSR1GAA | |
| SCHEMBL5529311 | 0.79 | NPSR1 (0.41) | FAAHNAAAHSD17B10NPSR1GAA | |
| SCHEMBL9603601 | 0.77 | FAAH (0.36) | FAAHNAAAHSD17B10NPSR1GAA | |
| SCHEMBL912170 | 0.76 | ALDH1A1 (0.40) | FAAHNAAAHSD17B10NPSR1GAA | |
| SCHEMBL9781917 | 0.75 | ALDH1A1 (0.40) | FAAHNAAAHSD17B10NPSR1GAA | |
| SCHEMBL8166868 | 0.75 | NPSR1 (0.37) | FAAHNAAAHSD17B10NPSR1GAA | |
| SCHEMBL417979 | 0.75 | NPSR1 (0.37) | FAAHNAAAHSD17B10NPSR1GAA | |
| SCHEMBL11027876 | 0.74 | KMT2A (0.44) | FAAHNAAANPSR1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021678-B1 | 1-SULPHO-2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 1984-11-07 | — | — | EP | disclosed |