Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971017 | 0.77 | FAAH (0.39) | FAAHNAAAALDH1A1POLBGAA | |
| SCHEMBL11076055 | 0.77 | FAAH (0.46) | FAAHNAAAALDH1A1POLBGAA | |
| SCHEMBL8718626 | 0.77 | FAAH (0.39) | FAAHNAAAALDH1A1POLBGAA | |
| SCHEMBL912170 | 0.72 | ALDH1A1 (0.40) | FAAHNAAAALDH1A1POLBGAA | |
| SCHEMBL9781917 | 0.71 | ALDH1A1 (0.40) | FAAHNAAAALDH1A1POLBGAA | |
| SCHEMBL5529311 | 0.71 | NPSR1 (0.41) | FAAHNAAAALDH1A1POLBGAA | |
| SCHEMBL417979 | 0.71 | NPSR1 (0.37) | FAAHNAAAALDH1A1POLBGAA | |
| SCHEMBL8166868 | 0.71 | NPSR1 (0.37) | FAAHNAAAALDH1A1POLBGAA | |
| SCHEMBL1243795 | 0.69 | HDAC3 (0.37) | ALDH1A1POLBGAANPSR1 | |
| SCHEMBL29654087 | 0.68 | NPSR1 (0.35) | FAAHNAAAALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215435-B1 | 2-OXA-ISOCEPHEM COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | claimed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | claimed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | claimed |
| JP-54106490-A | — | — | None | — | — | JP | disclosed |
| EP-0215435-B1 | 2-OXA-ISOCEPHEM COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |
| JP-S54106490-A | PROPARGYLGLYCINE DERIVATIVE AND ITS PREPARATION | NIPPON CHEMIPHAR CO LTD | 1979-08-21 | — | — | JP | disclosed |