SCHEMBL4971017

SCHEMBL4971017

NCC(=O)N1CCNC(=O)C1=O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.39
NAAA Q02083 1/20 0.39
GAA P10253 2/20 0.36
HSD17B10 Q99714 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
MAPT P10636 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8718626 0.81 FAAH (0.39) FAAHNAAAGAAHSD17B10NPSR1
SCHEMBL11076055 0.81 FAAH (0.46) FAAHNAAAGAAHSD17B10NPSR1
SCHEMBL417979 0.79 NPSR1 (0.37) FAAHNAAAGAAHSD17B10NPSR1
SCHEMBL9603601 0.77 FAAH (0.36) FAAHNAAAGAAHSD17B10NPSR1
SCHEMBL912170 0.76 ALDH1A1 (0.40) FAAHNAAAGAAHSD17B10NPSR1
SCHEMBL29654087 0.76 NPSR1 (0.35) FAAHNAAAGAANPSR1ALDH1A1
SCHEMBL5529311 0.75 NPSR1 (0.41) FAAHNAAAGAAHSD17B10NPSR1
SCHEMBL9781917 0.75 ALDH1A1 (0.40) FAAHNAAAGAAHSD17B10NPSR1
SCHEMBL8166868 0.75 NPSR1 (0.37) FAAHNAAAGAAHSD17B10NPSR1
SCHEMBL30016924 0.71 NPSR1 (0.36) FAAHNAAAHSD17B10NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022182415-A1 HIMASTATIN DERIVATIVES, AND PROCESSES OF PREPARATION THEREOF, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-09-01 WO disclosed
EP-2736879-B2 GENERAL METHOD FOR PREPARING FATTY ACYL AMIDO BASED SURFACTANTS UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2019-07-03 EP disclosed
CN-103842489-B Surfactant concentrate based on fatty acyl amino 荷兰联合利华有限公司 2016-08-17 CN disclosed
EP-2736878-B1 METHOD FOR PREPARING FATTY ACYL AMIDO CARBOXYLIC ACID BASED SURFACTANTS UNILEVER PLC NO 41424 (GB) 2016-06-22 EP disclosed
CN-103946209-B Compositions containing amino acid salts UNILEVER NEDERLAND B.V. (NL) 2016-06-01 CN disclosed
EP-2737039-B1 FATTY ACYL AMIDO BASED SURFACTANT CONCENTRATES UNILEVER PLC (GB) 2016-03-30 EP disclosed
EP-2736879-B1 GENERAL METHOD FOR PREPARING FATTY ACYL AMIDO BASED SURFACTANTS UNILEVER PLC NO 41424 (GB) 2015-11-18 EP disclosed
CN-103649043-B For the preparation of the method for the tensio-active agent based on fatty acyl amino carboxylic acid UNILEVER NEDERLAND B.V. (NL) 2015-09-23 CN disclosed
EP-2736877-B1 AMINO ACID SALT CONTAINING COMPOSITIONS UNILEVER PLC NO 41424 (GB) 2015-09-16 EP disclosed
US-8981134-B2 Amino acid salt containing compositions CONOPCO, INC. (US) 2015-03-17 US disclosed
US-20130030200-A1 FATTY ACYL AMIDO BASED SURFACTANT CONCENTRATES CONOPCO, INC., D/B/A UNILEVER (US) 2013-01-31 US disclosed
US-20130030201-A1 METHOD FOR PREPARING FATTY ACYL AMIDO CARBOXYLIC ACID BASED SURFACTANTS CONOPCO, INC., D/B/A UNILEVER (US) 2013-01-31 US disclosed
US-20130030203-A1 GENERAL METHOD FOR PREPARING FATTY ACYL AMIDO BASED SURFACTANTS CONOPCO, INC., D/B/A UNILEVER (US) 2013-01-31 US disclosed
US-20130030198-A1 GENERAL METHOD FOR PREPARING FATTY ACYL AMIDO BASED SURFACTANTS CONOPCO, INC., D/B/A UNILEVER (US) 2013-01-31 US disclosed
US-20130030202-A1 METHOD FOR PREPARING FATTY ACYL AMIDO CARBOXYLIC ACID BASED SURFACTANTS CONOPCO, INC., D/B/A UNILEVER (US) 2013-01-31 US disclosed
US-20130030199-A1 AMINO ACID SALT CONTAINING COMPOSITIONS CONOPCO, INC., D/B/A UNILEVER (US) 2013-01-31 US disclosed
WO-2013014268-A1 METHOD FOR PREPARING FATTY ACYL AMIDO CARBOXYLIC ACID BASED SURFACTANTS UNILEVER PLC (GB) 2013-01-31 WO disclosed
EP-1672055-B1 DETERGENT COMPOSITIONS AND PROCESSES FOR THE PRODUCTION THEREOF AJINOMOTO KK (JP) 2008-10-01 EP disclosed
US-20060239952-A1 Cleaning composition and method for preparing the same AJINOMOTO CO., INC. (JP) 2006-10-26 US disclosed
EP-1672055-A1 DETERGENT COMPOSITIONS AND PROCESSES FOR THE PRODUCTION THEREOF Ajinomoto Co., Inc. (JP) 2006-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130030200-A1 FATTY ACYL AMIDO BASED SURFACTANT CONCENTRATES APOB, LYPLA2, LIPC FAAH 331/4885NAAA 126/4885GAA 1730/4885
US-20130030198-A1 GENERAL METHOD FOR PREPARING FATTY ACYL AMIDO BASED SURFACTANTS ACSL6, ACSL3, LIPC FAAH 146/4885NAAA 34/4885GAA 462/4885
US-20130030201-A1 METHOD FOR PREPARING FATTY ACYL AMIDO CARBOXYLIC ACID BASED SURFACTANTS UGCG, GK, SGMS2 FAAH 98/4885NAAA 55/4885GAA 1163/4885
US-20130030203-A1 GENERAL METHOD FOR PREPARING FATTY ACYL AMIDO BASED SURFACTANTS ACSL3, ACSL6, ACSL1 FAAH 140/4885NAAA 42/4885GAA 720/4885
US-20130030199-A1 AMINO ACID SALT CONTAINING COMPOSITIONS SLC38A7, SLC6A15, SLC7A5 FAAH 265/4885NAAA 15/4885GAA 2535/4885
US-20130030202-A1 METHOD FOR PREPARING FATTY ACYL AMIDO CARBOXYLIC ACID BASED SURFACTANTS GK, UGCG, DGAT2 FAAH 151/4885NAAA 31/4885GAA 971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.