Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077460 | 0.89 | MAPK1 (0.35) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL11075195 | 0.87 | KMT2A (0.39) | DHODHGRIN2BPIK3CAMAPK1MAPK8 | |
| SCHEMBL11076390 | 0.87 | MAPT (0.43) | NPC1RAB9A | |
| SCHEMBL11078682 | 0.83 | NPC1 (0.35) | GRIN2BPIK3CAMAPK1MAPK8MAPK9 | |
| SCHEMBL11084393 | 0.75 | MEN1 (0.39) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL11206053 | 0.72 | MEN1 (0.49) | — | |
| SCHEMBL11208046 | 0.72 | LMNA (0.38) | — | |
| SCHEMBL11082728 | 0.71 | MEN1 (0.36) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL11084575 | 0.69 | MEN1 (0.34) | GRIN2BPIK3CAMAPK1MAPK8MAPK9 | |
| SCHEMBL11081532 | 0.68 | NPC1 (0.32) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4462994-A | O-ARYLPHOSPHATE DERIVATIVE OF QUINOXALINE | NISSAN CHEMICAL INDUSTRIES, INC. (JP) | 1984-07-31 | — | — | US | claimed |
| EP-0065287-A2 | N-containing heterocyclic ring-substituted O-arylphosphate derivatives, preparation thereof, and insecticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-11-24 | — | — | EP | claimed |
| US-4462994-A | O-ARYLPHOSPHATE DERIVATIVE OF QUINOXALINE | NISSAN CHEMICAL INDUSTRIES, INC. (JP) | 1984-07-31 | — | — | US | disclosed |