Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076390 | 0.89 | MAPT (0.43) | NPC1RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11077460 | 0.86 | MAPK1 (0.35) | NPC1RAB9AMAPTMAPK1PIK3CA | |
| SCHEMBL11075195 | 0.86 | KMT2A (0.39) | NPC1RAB9AMAPTMAPK1PIK3CA | |
| SCHEMBL11077871 | 0.83 | TDO2 (0.34) | NPC1RAB9AMAPK1PIK3CAMAPK8 | |
| SCHEMBL11081532 | 0.83 | NPC1 (0.32) | NPC1RAB9AKMT2A | |
| SCHEMBL11084400 | 0.77 | MEN1 (0.43) | NPC1RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10939357 | 0.75 | HTT (0.36) | NPC1RAB9AMAPTSMN1; SMN2NFKB1 | |
| SCHEMBL11084393 | 0.73 | MEN1 (0.39) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL11784939 | 0.72 | MEN1 (0.40) | NPC1RAB9AMAPK1SMN1; SMN2KMT2A | |
| Profenofos SCHEMBL25281 | 0.71 | MEN1 (0.52) | NPC1RAB9AKDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4462994-A | O-ARYLPHOSPHATE DERIVATIVE OF QUINOXALINE | NISSAN CHEMICAL INDUSTRIES, INC. (JP) | 1984-07-31 | — | — | US | claimed |
| EP-0065287-A2 | N-containing heterocyclic ring-substituted O-arylphosphate derivatives, preparation thereof, and insecticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-11-24 | — | — | EP | claimed |
| US-4462994-A | O-ARYLPHOSPHATE DERIVATIVE OF QUINOXALINE | NISSAN CHEMICAL INDUSTRIES, INC. (JP) | 1984-07-31 | — | — | US | disclosed |
| EP-0065287-A2 | N-containing heterocyclic ring-substituted O-arylphosphate derivatives, preparation thereof, and insecticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-11-24 | — | — | EP | disclosed |