Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18484513 | 0.77 | GABRA1 (0.50) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL11077794 | 0.74 | ALDH1A1 (0.39) | MEN1KMT2AKDM4EMAPTCCR2 | |
| SCHEMBL10596385 | 0.70 | CYP3A4 (0.38) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL8091206 | 0.70 | POLB (0.49) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL25993850 | 0.69 | KDM4E (0.44) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL13689698 | 0.68 | MEN1 (0.59) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL9664124 | 0.67 | ALDH1A1 (0.50) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL992504 | 0.67 | ALDH1A1 (0.48) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL10455909 | 0.65 | ALDH1A1 (0.50) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL10781975 | 0.65 | TSHR (0.41) | MEN1KMT2AKDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111146-A2 | Anti-mycotic hydroxyalkyl-azolyl derivatives | BAYER AG (DE) | 1984-06-20 | — | — | EP | disclosed |