Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | AOC2 | O75106 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2983751 | 0.98 | ALOX15 (0.47) | ALOX15LTA4HTSHRMAPK10TDP1 | |
| SCHEMBL13696728 | 0.87 | LTA4H (0.51) | LTA4H | |
| Hydrochloric Acid SCHEMBL2826316 | 0.80 | PMP22 (0.47) | TSHRWDR5KDM4EALDH1A1TP53 | |
| SCHEMBL5506784 | 0.79 | KMT2A (0.55) | TDP1SMN1; SMN2RAB9AMAOBALDH1A1 | |
| Hydrochloric Acid SCHEMBL28014731 | 0.78 | ALOX15 (0.50) | ALOX15TSHRMAPK10SMN1; SMN2NPC1 | |
| SCHEMBL13629002 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2NPC1RAB9AMAOBWDR5 | |
| SCHEMBL377638 | 0.77 | GAA (0.65) | ALOX15TSHRMAPK10TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2983753 | 0.77 | ALOX15 (0.48) | ALOX15LTA4HTSHRMAPK10TDP1 | |
| Hydrochloric Acid SCHEMBL11539234 | 0.76 | PMP22 (0.43) | LTA4HTSHRSMN1; SMN2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL4433395 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448968-A | HYDROLYSIS OF A 2-ALKOXY-1,3,4,-THIADIAZOLE USING HYDROCHLORIC ACID AND A NONAQUEOUS SOLVENT | CIBA-GEIGY CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |