Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182996 | 0.87 | ALDH1A1 (0.76) | DRD2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL2834503 | 0.86 | ALDH1A1 (0.79) | DRD2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL11756285 | 0.85 | HTR1A (0.70) | DRD2HTR1AHTR2ASLC6A4HTR7 | |
| SCHEMBL13089316 | 0.85 | ALDH1A1 (0.66) | DRD2ALDH1A1KMT2AHTR7 | |
| SCHEMBL7385393 | 0.84 | DRD2 (0.58) | DRD2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7386508 | 0.83 | MAPT (0.61) | DRD2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7390493 | 0.83 | MAPT (0.61) | DRD2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7390501 | 0.83 | MAPT (0.61) | DRD2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7393085 | 0.82 | DRD2 (0.60) | DRD2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL16026463 | 0.81 | KMT2A (0.83) | ALDH1A1KMT2AMAPTGFERHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430342-A | CARDIOVASCULAR DISORDERS | Hidaka, Hiroyoshi (JP) | 1984-02-07 | — | — | US | disclosed |
| US-4421754-A | ANTICOAGULANTS, MUSCLE RELAXANT | Hidaka, Hiroyoshi (JP) | 1983-12-20 | — | — | US | disclosed |
| EP-0076952-A1 | N-acyl-3-(4-(benzoylalkyl)piperazin-1-yl)-sydnonimine compound, process for production thereof, and use thereof | Hidaka, Hiroyoshi (JP) | 1983-04-20 | — | — | EP | disclosed |
| EP-0073345-A2 | Sydnonimine derivatives, process for production thereof, and use thereof | Hidaka, Hiroyoshi (JP) | 1983-03-09 | — | — | EP | disclosed |