Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847713 | 0.87 | LMNA (0.46) | GAATDP1ADRB1ADRA1ALMNA | |
| SCHEMBL28140070 | 0.86 | SLC22A1 (0.42) | GAATDP1ADRB1MIFHTR2A | |
| SCHEMBL18496734 | 0.83 | OPRD1 (0.44) | ADRB1MIFHTR2AADRA1AHTR2B | |
| SCHEMBL15270484 | 0.83 | MMP8 (0.44) | GAATDP1LMNAKDM4EPKM | |
| SCHEMBL3905021 | 0.82 | ADRB1 (0.45) | GAAADRB1MIFHTR2AADRA1A | |
| SCHEMBL5212783 | 0.82 | KYNU (0.49) | GAAADRB1MIFHTR2AADRA1A | |
| SCHEMBL31074078 | 0.82 | ADRB1 (0.45) | GAAADRB1MIFHTR2AADRA1A | |
| SCHEMBL5212789 | 0.82 | KYNU (0.49) | GAAADRB1MIFHTR2AADRA1A | |
| SCHEMBL29687004 | 0.81 | KYNU (0.51) | GAAADRB1ADRA1ALMNAKDM4E | |
| SCHEMBL1820061 | 0.81 | KYNU (0.51) | GAAADRB1ADRA1ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450115-A | ADRENERGIC BLOCKING AGENTS; HYPOTENSIVE AND CARDIOTONIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1984-05-22 | — | — | US | disclosed |
| US-4381398-A | Amino-alcohol derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-04-26 | — | — | US | disclosed |