Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21009691 | 0.82 | MEN1 (0.65) | ACHEPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9871627 | 0.80 | SIGMAR1 (0.60) | MEN1KMT2AALDH1A1KDM4EFAAH | |
| SCHEMBL1671165 | 0.79 | EPHX2 (0.56) | ACHEMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL20457589 | 0.78 | ACHE (0.57) | ACHEALDH1A1KDM4EHTTFAAH | |
| SCHEMBL11002867 | 0.77 | ALDH1A1 (0.55) | ACHEPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL593734 | 0.77 | SIGMAR1 (0.62) | ACHEPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL29756483 | 0.77 | SIGMAR1 (0.62) | ACHEPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9829721 | 0.76 | MEN1 (0.54) | ACHEPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL10232320 | 0.76 | LMNA (0.48) | ACHEPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL12626055 | 0.75 | ALDH1A1 (0.57) | ACHEPOLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077288-A | Adrenergic, serotonin and histamine antagonist | ADIR ET COMPAGNIE (FR) | 1991-12-31 | — | — | US | disclosed |