Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049737 | 0.84 | TDP1 (0.45) | TDP1MEN1KMT2ACASP1ALDH1A1 | |
| SCHEMBL28287911 | 0.82 | TDP1 (0.40) | TDP1MEN1KMT2ACASP1ALDH1A1 | |
| SCHEMBL16093518 | 0.81 | MEN1 (0.42) | TDP1MEN1KMT2ACASP1ALDH1A1 | |
| SCHEMBL18159716 | 0.81 | TDP1 (0.39) | TDP1MEN1KMT2ACASP1ALDH1A1 | |
| SCHEMBL27577559 | 0.80 | CASP1 (0.44) | TDP1CASP1 | |
| SCHEMBL27577561 | 0.80 | CASP1 (0.44) | TDP1CASP1 | |
| SCHEMBL8260665 | 0.80 | FAAH (0.38) | TDP1MEN1KMT2ACASP1FAAH | |
| SCHEMBL20663472 | 0.80 | FAAH (0.38) | TDP1MEN1KMT2ACASP1FAAH | |
| SCHEMBL17324271 | 0.79 | GFPT1 (0.45) | MEN1KMT2ACASP1MAPTCACNA1B | |
| SCHEMBL9313394 | 0.79 | TDP1 (0.38) | TDP1MEN1KMT2ACASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125208-A1 | Amino-lower-alkyl-penem derivatives, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1984-11-14 | — | — | EP | disclosed |