SCHEMBL8260665

SCHEMBL8260665

C=CCOC(=O)NCCCCC(C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
TGM2 P21980 5/20 0.37
LTA4H P09960 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ACHE P22303 2/20 0.37
BLM P54132 1/20 0.37
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
ERN1 O75460 1/20 0.36
BRD4 O60885 1/20 0.36
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
FOLH1 Q04609 1/20 0.35
ACE2 Q9BYF1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20663472 1.00 FAAH (0.38) FAAHMEN1GAAKMT2ATGM2
SCHEMBL16093518 0.95 MEN1 (0.42) FAAHMEN1GAAKMT2ATGM2
SCHEMBL19130730 0.88 BRD4 (0.38) FAAHTGM2TDP1ACHEMAPT
SCHEMBL19414915 0.87 TDP1 (0.36) FAAHTGM2TDP1ACHEMAPT
SCHEMBL15631792 0.83 TGM2 (0.43) MEN1GAAKMT2ATGM2CASP1
SCHEMBL9966613 0.82 DDAH1 (0.52) TGM2ERN1
SCHEMBL458808 0.82 DDAH1 (0.52) TGM2ERN1
SCHEMBL30033086 0.82 DDAH1 (0.52) TGM2ERN1
SCHEMBL23705400 0.81 TGM2 (0.52) TGM2CASP1FOLH1
SCHEMBL23705401 0.81 TGM2 (0.52) TGM2CASP1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230374045-A1 AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS PROTOMER TECHNOLOGIES INC. 2023-11-23 US disclosed
WO-2006062685-A2 NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR AFFYMAX, INC. (US) 2006-06-15 WO disclosed
WO-2006060148-A2 NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR AFFYMAX, INC. (US) 2006-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230374045-A1 AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS IAPP, GPR119, INSR FAAH 4658/4885MEN1 567/4885GAA 48/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.