Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 7/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084158 | 0.78 | ALDH1A1 (0.41) | MAPTKMT2AKIF11CYP2D6CHRM2 | |
| Piperazine SCHEMBL10994605 | 0.73 | KMT2A (0.39) | MAPTKMT2AKIF11CYP2D6CHRM2 | |
| SCHEMBL10994601 | 0.71 | ALDH1A1 (0.47) | MAPTKMT2ACYP2D6CHRM2CHRM3 | |
| SCHEMBL10988392 | 0.70 | CNR1 (0.39) | MAPTKMT2AKIF11LMNAHTT | |
| SCHEMBL5617129 | 0.68 | KIF11 (0.44) | MAPTKMT2AKIF11CYP2D6CHRM2 | |
| SCHEMBL10693506 | 0.67 | MAPT (0.52) | MAPTKMT2ACYP2D6CHRM2CHRM3 | |
| SCHEMBL28014000 | 0.66 | CYP2C19 (0.46) | MAPTKMT2AKIF11CYP2D6KCNH2 | |
| SCHEMBL28033810 | 0.66 | MAPT (0.47) | MAPTKMT2AKIF11CYP2D6CHRM2 | |
| SCHEMBL10989943 | 0.66 | MAPT (0.55) | MAPTKMT2ACYP2D6CHRM2CHRM3 | |
| SCHEMBL11247 | 0.65 | KMT2A (0.46) | MAPTKMT2AKIF11CYP2D6CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |