Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079669 | 0.78 | MAPT (0.37) | ALDH1A1MAPTKMT2AKIF11LMNA | |
| Piperazine SCHEMBL10994605 | 0.77 | KMT2A (0.39) | ALDH1A1MAPTKMT2AKIF11LMNA | |
| SCHEMBL8459554 | 0.75 | ALDH1A1 (0.44) | ALDH1A1OPRM1CYP2D6CHRM1CHRM3 | |
| SCHEMBL10994601 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2ALMNAOPRM1 | |
| SCHEMBL873380 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2APTGS2KEAP1 | |
| SCHEMBL4560574 | 0.73 | MAPT (0.52) | ALDH1A1MAPTKMT2AKIF11LMNA | |
| SCHEMBL4558956 | 0.73 | KIF11 (0.46) | ALDH1A1MAPTKMT2AKIF11LMNA | |
| SCHEMBL6803588 | 0.72 | HDAC3 (0.50) | ALDH1A1MAPTKMT2AKIF11LMNA | |
| SCHEMBL23256417 | 0.72 | MAPT (0.46) | MAPTKMT2AKIF11CHRM1CYP2C19 | |
| SCHEMBL5617129 | 0.72 | KIF11 (0.44) | MAPTKMT2AKIF11LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |