Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 7/20 | 0.41 |
| ▸ | CTSB | P07858 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077487 | 0.92 | CTSS (0.43) | CTSSCTSLOPRK1ATMCTSK | |
| SCHEMBL11080033 | 0.88 | CTSS (0.40) | CTSSCTSLOPRK1ATMCTSK | |
| SCHEMBL8743305 | 0.83 | PLCG1 (0.41) | CTSSCTSKCTSBALDH1A1 | |
| SCHEMBL8743301 | 0.83 | PLCG1 (0.41) | CTSSCTSKCTSBALDH1A1 | |
| SCHEMBL11080922 | 0.82 | CTSS (0.43) | CTSSCTSLOPRK1ATMCTSK | |
| SCHEMBL11080633 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HSD17B10BLMKMT2ACYP3A4 | |
| SCHEMBL11084586 | 0.79 | HSD17B10 (0.39) | CTSSCTSKCTSBALDH1A1HSD17B10 | |
| SCHEMBL11081308 | 0.79 | HSD17B10 (0.44) | ALDH1A1HSD17B10BLMKMT2ACYP3A4 | |
| SCHEMBL11670093 | 0.79 | PTGS1 (0.48) | CTSSCTSKMAPTHPGDMAPK1 | |
| SCHEMBL11670596 | 0.79 | PTGS1 (0.48) | CTSSCTSKMAPTHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040494-B1 | CARBAPENAMS AND CARBAPEN-2-EMS AND PROCESS THEREFOR | PFIZER INC. (US) | 1984-02-15 | — | — | EP | disclosed |
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | disclosed |