Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082666 | 1.00 | FPR3 (0.40) | FPR3FPR2SLC7A5CASRCA12 | |
| SCHEMBL6372575 | 0.84 | CASR (0.39) | FPR3FPR2CASRCA12CA1 | |
| SCHEMBL6372571 | 0.84 | CASR (0.39) | FPR3FPR2CASRCA12CA1 | |
| SCHEMBL11090585 | 0.81 | HDAC1 (0.45) | CASRCA12CA1CA2CA9 | |
| SCHEMBL11090583 | 0.81 | HDAC1 (0.45) | CASRCA12CA1CA2CA9 | |
| SCHEMBL11090579 | 0.81 | HDAC1 (0.45) | CASRCA12CA1CA2CA9 | |
| SCHEMBL4119738 | 0.79 | ALDH1A1 (0.47) | FPR3FPR2CA12CA1CA2 | |
| SCHEMBL11088028 | 0.78 | AKR1C3 (0.47) | FPR3FPR2SLC7A5CASRCA12 | |
| SCHEMBL303932 | 0.78 | PKM (0.46) | CA12CA1PTPRCL3MBTL1MAPT | |
| SCHEMBL4490577 | 0.78 | AKR1C3 (0.60) | CASRCA12CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |
| EP-0031794-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1981-07-08 | — | — | EP | disclosed |