SCHEMBL1108307

SCHEMBL1108307

NCCN1C(=O)CCC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
CA4 P22748 1/20 0.41
POLB P06746 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
FAAH O00519 1/20 0.37
MGLL Q99685 1/20 0.37
HEXA P06865 1/20 0.36
HEXB P07686 1/20 0.36
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
CA12 O43570 1/20 0.35
ALOX15 P16050 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4428365 0.84 MEN1 (0.44) CA1CA2CA9CA4POLB
SCHEMBL15468560 0.84 CA1 (0.36) CA1CA2CA9CA4HEXA
SCHEMBL19320493 0.83
SCHEMBL22394483 0.82 FAAH (0.46) CA1CA2CA9CA4POLB
Hydrochloric Acid SCHEMBL12501659 0.82 MEN1 (0.42) CA1CA2CA9CA4POLB
SCHEMBL8863095 0.82 POLB (0.43) CA1CA2CA9CA4POLB
Acrylic Acid SCHEMBL31065457 0.82 LMNA (0.37) CA1CA2CA9CA4POLB
SCHEMBL6565273 0.80 FAAH (0.44) CA1CA2CA9CA4POLB
SCHEMBL2907080 0.80 FAAH (0.44) CA1CA2CA9CA4POLB
SCHEMBL11875056 0.77 ACE2 (0.48) CA1CA2CA9CA4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220071917-A9 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2022-03-10 US claimed
US-20210228494-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2021-07-29 US claimed
EP-3703666-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS Universidade de Santiago de Compostela (ES) 2020-09-09 EP claimed
CN-1090973-C Technetium-99m labeled peptides for imaging DIATECH INC (US) 2002-09-18 CN claimed
CN-1087955-C Technetium-99m labeled imaging agents DIATECH INC (US) 2002-07-24 CN claimed
CN-1087630-C Radiolabeled compounds for imaging thrombi DIATECH INC (US) 2002-07-17 CN claimed
CN-1154071-A Radiolabeled compounds for imaging thrombi DIATECH INC (US) 1997-07-09 CN claimed
CN-1154072-A Technetium-99m labeled peptides for imaging DIATECH INC (US) 1997-07-09 CN claimed
EP-0775160-A1 CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGUES DIATECH, INC. (US) 1997-05-28 EP claimed
EP-0762901-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATECH, INC. (US) 1997-03-19 EP claimed
WO-1995033498-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATECH, INC. (US) 1995-12-14 WO claimed
EP-0665853-A1 MULTIMERIC POLYVALENT ANTITHROMBOTIC AGENTS Diatide, Inc. (US) 1995-08-09 EP claimed
EP-0649434-A1 RADIOACTIVELY-LABELED SOMATOSTATIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES Diatide, Inc. (US) 1995-04-26 EP claimed
EP-0644778-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING. DIATECH INC (US) 1995-03-29 EP claimed
EP-0370753-B1 Modified polyolefin particles and process for preparation thereof MITSUI PETROCHEMICAL IND (JP) 1995-01-18 EP claimed
EP-0630265-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING INFLAMMATION Diatide, Inc. (US) 1994-12-28 EP claimed
WO-1994028942-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING INFLAMMATION DIATECH, INC. (US) 1994-12-22 WO claimed
WO-1994007918-A1 MULTIMERIC POLYVALENT ANTITHROMBOTIC AGENTS DIATECH, INC. (US) 1994-04-14 WO claimed
CN-1043144-A Modified polyolefin particles and preparation method thereof MITSUI PETROCHEMICAL IND (JP) 1990-06-20 CN claimed
EP-0370753-A2 Modified polyolefin particles and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-05-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210228494-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS LNPEP, CLIC1, CLSPN CA1 159/4885CA2 770/4885CA9 468/4885
US-20220071917-A9 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS LNPEP, CLIC1, CLSPN CA1 159/4885CA2 770/4885CA9 468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.