Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 1/20 | 0.36 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083125 | 1.00 | MTTP (0.36) | MTTPSOAT2SOAT1KMT2A | |
| SCHEMBL11085690 | 0.84 | DRD2 (0.42) | MTTP | |
| SCHEMBL11208949 | 0.82 | SIGMAR1 (0.41) | MTTP | |
| SCHEMBL10778064 | 0.79 | POLB (0.34) | SOAT2SOAT1KMT2A | |
| SCHEMBL10778069 | 0.79 | POLB (0.34) | SOAT2SOAT1KMT2A | |
| SCHEMBL10995584 | 0.79 | APEX1 (0.40) | MTTPKMT2A | |
| SCHEMBL11089773 | 0.78 | MAOA (0.49) | KMT2A | |
| SCHEMBL11083146 | 0.77 | PDK2 (0.36) | MTTP | |
| SCHEMBL11019261 | 0.76 | APEX1 (0.36) | MTTPKMT2A | |
| SCHEMBL11086275 | 0.72 | APEX1 (0.41) | MTTPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452745-A | ANTIARRHYTHMIA AGENTS | ELI LILLY AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| US-4382093-A | 9-Aminoalkylfluorenes | ELI LILLY AND COMPANY (US) | 1983-05-03 | — | — | US | disclosed |
| US-4277495-A | FLUORENE 9-AMINOALKYL-9-CARBOXYLIC ACIDS OR ESTERS | ELI LILLY AND COMPANY (US) | 1981-07-07 | — | — | US | disclosed |
| EP-0018076-A1 | 9-Aminoalkylfluorenes, process therefor and antiarrhythmic formulations thereof | ELI LILLY AND COMPANY (US) | 1980-10-29 | — | — | EP | disclosed |