Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.51 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCKDK | O14874 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077508 | 0.78 | LIMK1 (0.49) | HRH4LIMK1MAPTKMT2AMEN1 | |
| SCHEMBL11082423 | 0.75 | PIM1 (0.40) | HRH4LIMK1MAPTSMN1; SMN2PIM1 | |
| SCHEMBL15223343 | 0.69 | BCKDK (0.50) | HRH4LIMK1MAPTKMT2AMEN1 | |
| SCHEMBL605516 | 0.68 | HRH4 (1.00) | HRH4 | |
| SCHEMBL11125003 | 0.68 | AHR (0.42) | HRH4KMT2AALDH1A1MCL1 | |
| SCHEMBL20356905 | 0.66 | LIMK1 (0.53) | HRH4LIMK1KMT2AALDH1A1 | |
| SCHEMBL20363803 | 0.66 | LIMK1 (0.44) | HRH4LIMK1MAPTKMT2AMEN1 | |
| SCHEMBL21835885 | 0.66 | HRH4 (0.46) | HRH4LIMK1MAPTKMT2AMEN1 | |
| SCHEMBL11126598 | 0.65 | ALDH1A1 (0.51) | HRH4KMT2AALDH1A1PIM1PIM2 | |
| SCHEMBL4922527 | 0.65 | BCKDK (0.53) | MAPTKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431657-A | Analgesic compositions consisting of 2H-benzothieno[3,2-c]pyrazol-3-amine derivatives | AYERST, MCKENNA & HARRISON INC. (CA) | 1984-02-14 | — | — | US | disclosed |