SCHEMBL1108326

SCHEMBL1108326

CCCC1OCCC(C)O1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.38
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28330247 0.86 EPHX1 (0.52) EPHX1
SCHEMBL31473475 0.84 EPHX1 (0.55) EPHX1
SCHEMBL10827128 0.84 EPHX1 (0.55) EPHX1
SCHEMBL8533836 0.82
SCHEMBL11395769 0.81
SCHEMBL14322373 0.78 EPHX1 (0.38) EPHX1CA1CA2CA4
SCHEMBL8838402 0.78
SCHEMBL30531154 0.77
SCHEMBL14272686 0.77
SCHEMBL1838332 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861395-A Polyester with acetal group in main chain and preparation method thereof 浙江大学 2021-12-31 CN claimed
US-9388105-B2 Production of hydroxy ether hydrocarbons by liquid phase hydrogenolysis of cyclic acetals or cyclic ketals EASTMAN CHEMICAL COMPANY (US) 2016-07-12 US claimed
US-8969598-B2 Production of cyclic acetals or ketals using liquid-phase acid catalysts EASTMAN CHEMICAL COMPANY (US) 2015-03-03 US claimed
US-8829207-B2 Production of cyclic acetals by reactive distillation EASTMAN CHEMICAL COMPANY (US) 2014-09-09 US claimed
US-8829206-B2 Production of cyclic acetals or ketals using solid acid catalysts EASTMAN CHEMICAL COMPANY (US) 2014-09-09 US claimed
WO-2012177417-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO claimed
WO-2012177469-A1 PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO claimed
WO-2012177485-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING LIQUID-PHASE ACID CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO claimed
US-20120330034-A1 PRODUCTION OF CYCLIC ACETALS BY REACTIVE DISTILLATION EASTMAN CHEMICAL COMPANY (US) 2012-12-27 US claimed
US-20120330033-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING LIQUID-PHASE ACID CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 US claimed
US-20120330069-A1 PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 US claimed
US-20120330032-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 US claimed
EP-1427458-B1 TREATING SURFACES TO ENHANCE BIO-COMPATIBILITY BAYER MATERIALSCIENCE AG (DE) 2010-11-24 EP claimed
US-20100247931-A1 TREATING SURFACES TO ENHANCE BIO-COMPATIBILITY AL-LAMEE KADEM GAYED 2010-09-30 US claimed
US-20040241325-A1 Treating surfaces to enhance bio-compatibility BAYER MATERIALSCIENCE AG (DE) 2004-12-02 US claimed
EP-1427458-A1 TREATING SURFACES TO ENHANCE BIO-COMPATIBILITY PolyBioMed Limited (GB) 2004-06-16 EP claimed
WO-2003024500-A1 TREATING SURFACES TO ENHANCE BIO-COMPATIBILITY POLYBIOMED LIMITED (GB) 2003-03-27 WO claimed
CN-113861395-B Polyester with acetal group in main chain and preparation method thereof 浙江大学 2022-11-18 CN disclosed
US-7201938-B2 Thermosensitive stencil paper and method of producing the same RICOH COMPANY, LTD. (JP) 2007-04-10 US disclosed
EP-1750175-A1 POSITIVE PHOTOSENSITIVE COMPOSITION THINK LABORATORY CO., LTD. (JP) 2007-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120330069-A1 PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS CCNE2, CCNH, HRH2 EPHX1 77/4885CA1 216/4885CA2 660/4885
US-20120330032-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS PKLR, AKR1C4, AKR1C2 EPHX1 186/4885CA1 188/4885CA2 1219/4885
US-20120330034-A1 PRODUCTION OF CYCLIC ACETALS BY REACTIVE DISTILLATION ADH1C, ADH1A, SORD EPHX1 464/4885CA1 186/4885CA2 877/4885
US-20120330033-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING LIQUID-PHASE ACID CATALYSTS PKLR, KHK, PHYKPL EPHX1 352/4885CA1 881/4885CA2 1729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.