Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.62 |
| ▸ | CTSS | P25774 | 6/20 | 0.56 |
| ▸ | CTSK | P43235 | 5/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.54 |
| ▸ | ITGAV | P06756 | 1/20 | 0.54 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | PPARG | P37231 | 5/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.53 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730038 | 1.00 | ACE (0.62) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL376103 | 1.00 | ACE (0.62) | ACEITGB3ITGA2BCTSSCTSK | |
| Hydrochloric Acid SCHEMBL27338139 | 0.99 | ACE (0.61) | ACEITGB3ITGA2BCTSSCTSK | |
| Hydrochloric Acid SCHEMBL27338140 | 0.99 | ACE (0.61) | ACEITGB3ITGA2BCTSSCTSK | |
| Acetic Acid SCHEMBL2729607 | 0.97 | ACE (0.60) | ACEITGB3ITGA2BCTSSCTSK | |
| Acetic Acid SCHEMBL2729608 | 0.97 | ACE (0.60) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL20187263 | 0.89 | CTSS (0.66) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL18228975 | 0.89 | CTSS (0.66) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL1009069 | 0.89 | ACE (0.62) | ACEITGB3ITGA2BCTSSCTSK | |
| SCHEMBL19575827 | 0.89 | REN (0.54) | ACEITGB3ITGA2BCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874803-A | Antibacterial dendritic polyester polymer and preparation method and application thereof | 清华大学深圳国际研究生院 | 2023-10-13 | — | — | CN | claimed |
| CN-116041210-A | Chiral nano material and preparation method thereof | 南京工业大学 | 2023-05-02 | — | — | CN | claimed |
| US-20110076718-A1 | IN VIVO INCORPORATION OF AN UNNATURAL AMINO ACID COMPRISING A 1,2-AMINOTHIOL GROUP | THE SCRIPPS RESEARCH INSTITUTE | 2011-03-31 | — | — | US | claimed |
| WO-2009151491-A9 | IN VIVO INCORPORATION OF AN UNNATURAL AMINO ACID COMPRISING A 1,2-AMINOTHIOL GROUP | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-01-28 | — | — | WO | claimed |
| WO-2009151491-A2 | IN VIVO INCORPORATION OF AN UNNATURAL AMINO ACID COMPRISING A 1,2-AMINOTHIOL GROUP | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-12-17 | — | — | WO | claimed |
| CN-117480164-B | Factor XIa inhibitor and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-4347615-A1 | PROCESS FOR MAKING MELFLUFEN OR A SALT THEREOF | Synthon B.V. (NL) | 2024-04-10 | — | — | EP | disclosed |
| CN-117480164-A | Factor XIa inhibitor and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2023234425-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | ペプチドリーム株式会社 | 2023-12-07 | — | — | WO | disclosed |
| CN-116891437-A | Amino acid derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-116874803-A | Antibacterial dendritic polyester polymer and preparation method and application thereof | 清华大学深圳国际研究生院 | 2023-10-13 | — | — | CN | disclosed |
| CN-110475785-B | Peptide compound, method for producing same, composition for screening, and method for selecting peptide compound | 富士胶片株式会社 | 2023-06-13 | — | — | CN | disclosed |
| EP-1181266-A1 | SQUARIC ACID DERIVATIVES AS CELL ADHESION MOLECULES | Celltech R&D Limited (GB) | 2002-02-27 | — | — | EP | disclosed |
| WO-2001092256-A1 | 2,7-NAPHTHYRIDINE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2001-12-06 | — | — | WO | disclosed |
| WO-2000073260-A1 | SQUARIC ACID DERIVATIVES AS CELL ADHESION MOLECULES | CELLTECH R&D LIMITED (GB) | 2000-12-07 | — | — | WO | disclosed |
| US-6001810-A | ADDING STO A BIOLOGICAL SOLUTION CONTAINING RETROVIRAL PROTEASE AN INHIBITORY AMOUNT OF SHORT PEPTIDES OF SPECIFIEDAMINO ACID SEQUENCES | ELI LILLY AND COMPANY (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0736035-A4 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORP (US) | 1999-09-01 | — | — | EP | disclosed |
| EP-0736035-A1 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995015335-A2 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1995-06-08 | — | — | WO | disclosed |
| EP-0431784-A2 | Methods for treating retroviral infection | ELI LILLY AND COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110076718-A1 | IN VIVO INCORPORATION OF AN UNNATURAL AMINO ACID COMPRISING A 1,2-AMINOTHIOL GROUP | AARS1, NSUN3, NPEPPS | ACE 1053/4885ITGB3 3369/4885ITGA2B 4511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.