SCHEMBL376103

SCHEMBL376103

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(N)cc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.62
ITGB3 P05106 2/20 0.62
ITGA2B P08514 2/20 0.62
CTSS P25774 6/20 0.56
CTSK P43235 5/20 0.56
CTSL P07711 1/20 0.55
CTSB P07858 1/20 0.55
ITGB1 P05556 1/20 0.54
ITGAV P06756 1/20 0.54
ITGB5 P18084 1/20 0.54
PPARA Q07869 6/20 0.54
PPARG P37231 5/20 0.54
ITGA4 P13612 1/20 0.53
ITGB7 P26010 1/20 0.53
PTPN1 P18031 3/20 0.53
PPARD Q03181 2/20 0.52
CA2 P00918 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108339 1.00 ACE (0.62) ACEITGB3ITGA2BCTSSCTSK
SCHEMBL2730038 1.00 ACE (0.62) ACEITGB3ITGA2BCTSSCTSK
Hydrochloric Acid SCHEMBL27338139 0.99 ACE (0.61) ACEITGB3ITGA2BCTSSCTSK
Hydrochloric Acid SCHEMBL27338140 0.99 ACE (0.61) ACEITGB3ITGA2BCTSSCTSK
Acetic Acid SCHEMBL2729607 0.97 ACE (0.60) ACEITGB3ITGA2BCTSSCTSK
Acetic Acid SCHEMBL2729608 0.97 ACE (0.60) ACEITGB3ITGA2BCTSSCTSK
SCHEMBL20187263 0.89 CTSS (0.66) ACEITGB3ITGA2BCTSSCTSK
SCHEMBL18228975 0.89 CTSS (0.66) ACEITGB3ITGA2BCTSSCTSK
SCHEMBL1009069 0.89 ACE (0.62) ACEITGB3ITGA2BCTSSCTSK
SCHEMBL19575827 0.89 REN (0.54) ACEITGB3ITGA2BCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058821-A Prodrug designed based on tumor LAT1 transporter and preparation method thereof 广西中医药大学 2025-05-30 CN claimed
CN-118420494-B Hydroxyl radical reactive unnatural amino acid and preparation method and application thereof 北京大学深圳研究生院 2024-11-29 CN claimed
CN-116041210-A Chiral nano material and preparation method thereof 南京工业大学 2023-05-02 CN claimed
US-20110076718-A1 IN VIVO INCORPORATION OF AN UNNATURAL AMINO ACID COMPRISING A 1,2-AMINOTHIOL GROUP THE SCRIPPS RESEARCH INSTITUTE 2011-03-31 US claimed
WO-2009151491-A9 IN VIVO INCORPORATION OF AN UNNATURAL AMINO ACID COMPRISING A 1,2-AMINOTHIOL GROUP THE SCRIPPS RESEARCH INSTITUTE (US) 2010-01-28 WO claimed
WO-2009151491-A2 IN VIVO INCORPORATION OF AN UNNATURAL AMINO ACID COMPRISING A 1,2-AMINOTHIOL GROUP THE SCRIPPS RESEARCH INSTITUTE (US) 2009-12-17 WO claimed
WO-2026107097-A1 SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF ENLAZA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
US-12630808-B2 Modified archaeal family b polymerases Singular Genomics Systems, Inc. (US) 2026-05-19 US disclosed
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES SINGULAR GENOMICS SYSTEMS INC (US) 2026-05-07 US disclosed
US-20260117274-A1 ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF UNIV NEW YORK STATE RES FOUND (US) 2026-04-30 US disclosed
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents CIS BIOPHARMA AG (CH) 2026-02-24 US disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4677087-A1 NOVEL TREATMENTS FOR OCULAR DISORDERS Glaukos Corporation (US) 2026-01-14 EP disclosed
US-5565574-A BIOSYNTHESIS OF SYNTHETIC PEPTIDES THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1996-10-15 US disclosed
EP-0736035-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1996-10-09 EP disclosed
EP-0703900-A1 PROCESS FOR THE PREPARATION OF PHENYLALANINE DERIVATIVES OR HOMOLOGUES CONTAINING A GUANIDINO OR MODIFIED GUANIDINO GROUP USEFUL FOR THE PREPARATION GnRH OF ANTAGONISTIC PEPTIDES THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1996-04-03 EP disclosed
WO-1995015335-A2 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-08 WO disclosed
WO-1995000474-A1 PROCESS FOR THE PREPARATION OF PHENYLALANINE DERIVATIVES OR HOMOLOGUES CONTAINING A GUANIDINO OR MODIFIED GUANIDINO GROUP USEFUL FOR THE PREPARATION GnRH OF ANTAGONISTIC PEPTIDES THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1995-01-05 WO disclosed
US-5352796-A Chemical intermediates for gonadotropin-releasing hormone THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1994-10-04 US disclosed
EP-0431784-A2 Methods for treating retroviral infection ELI LILLY AND COMPANY (US) 1991-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents MSR1, CD47, SLC43A1 ACE 4044/4885ITGB3 156/4885ITGA2B 660/4885
US-12630808-B2 Modified archaeal family b polymerases SSU72, POLB, POLQ ACE 1258/4885ITGB3 3299/4885ITGA2B 1042/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 ACE 1944/4885ITGB3 2864/4885ITGA2B 3805/4885
US-20260117274-A1 ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF PTMS, PSMG3, PSMB3 ACE 1510/4885ITGB3 765/4885ITGA2B 3259/4885
US-20110076718-A1 IN VIVO INCORPORATION OF AN UNNATURAL AMINO ACID COMPRISING A 1,2-AMINOTHIOL GROUP AARS1, NSUN3, NPEPPS ACE 1053/4885ITGB3 3369/4885ITGA2B 4511/4885
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES DNMT3A, POLB, POLM ACE 663/4885ITGB3 4087/4885ITGA2B 2102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.