Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20659148 | 0.77 | LMNA (0.57) | HPGDRAB9ALMNATP53MAPT | |
| SCHEMBL3724012 | 0.73 | PLA2G2A (0.49) | HPGDLMNATP53MAPTMEN1 | |
| SCHEMBL1798141 | 0.72 | MAPT (0.49) | HPGDMAPTPDE4APDE4BPDE4C | |
| SCHEMBL16838230 | 0.72 | MAPT (0.57) | HPGDNPC1RAB9ALMNATP53 | |
| SCHEMBL10675396 | 0.69 | MAPT (0.42) | HPGDNPC1RAB9ALMNATP53 | |
| SCHEMBL15153224 | 0.69 | RAB9A (0.74) | HPGDNPC1RAB9AMAPTMEN1 | |
| SCHEMBL840603 | 0.68 | L3MBTL1 (0.43) | HPGDLMNATP53MAPTMEN1 | |
| SCHEMBL2956112 | 0.68 | L3MBTL1 (0.55) | HPGDLMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL10576705 | 0.68 | HPGD (0.56) | HPGDLMNATP53MAPTMEN1 | |
| SCHEMBL13861458 | 0.68 | HPGD (0.49) | HPGDNPC1RAB9ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424363-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1984-01-03 | — | — | US | disclosed |
| US-4354031-A | HERBICIDES | BASF ATIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |
| US-4316039-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |
| US-4260775-A | Substituted 3-aminopyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| EP-0002180-A1 | Substituted 3-aminopyrazoles, herbicides containing them and method for controlling undesirable growth of plants | BASF Aktiengesellschaft (DE) | 1979-06-13 | — | — | EP | disclosed |