Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088479 | 0.88 | NPSR1 (0.80) | MAPTNPSR1RAB9ACCNA2CDK2 | |
| SCHEMBL11084827 | 0.87 | RAB9A (0.61) | MAPTNPSR1RAB9AADORA3ADORA2A | |
| SCHEMBL11089737 | 0.82 | VNN1 (0.55) | NPSR1RAB9AADORA3ALDH1A1VNN1 | |
| SCHEMBL31141720 | 0.81 | VNN1 (0.64) | MAPTNPSR1RAB9ACCNA2CDK2 | |
| SCHEMBL11090074 | 0.81 | NPSR1 (0.54) | MAPTNPSR1RAB9AADORA3ADORA2A | |
| SCHEMBL11090716 | 0.80 | RAB9A (0.53) | MAPTNPSR1RAB9AKMT2AMEN1 | |
| SCHEMBL31141630 | 0.79 | RAB9A (0.63) | MAPTNPSR1RAB9AADORA1KMT2A | |
| SCHEMBL25263361 | 0.78 | MAPT (0.61) | MAPTNPSR1RAB9ACCNA2CDK2 | |
| SCHEMBL11092599 | 0.78 | RAB9A (0.50) | MAPTNPSR1RAB9AKMT2ATP53 | |
| SCHEMBL11086596 | 0.78 | RAB9A (0.64) | MAPTNPSR1RAB9AADORA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447422-A | Penicillins and compositions containing them | BEECHAM GROUP P.1.C. (GB) | 1984-05-08 | — | — | US | disclosed |
| EP-0067610-A1 | Penicillins, a process for their preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |