Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 7/20 | 0.44 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18297588 | 0.81 | CA2 (0.44) | PTGES2CA2CA9CA1CA12 | |
| SCHEMBL970204 | 0.81 | TRPV4 (0.42) | KDM4EALDH1A1HPGDHSD17B10SGK1 | |
| SCHEMBL15461576 | 0.81 | EPAS1 (0.45) | CYP2C9KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27731026 | 0.79 | STAT3 (0.42) | PTGES2CA2CA9CA1CA12 | |
| SCHEMBL2431935 | 0.78 | CYP1A2 (0.43) | PTGES2CA2CA9CA1CA12 | |
| SCHEMBL11091075 | 0.78 | SLC22A12 (0.46) | PTGES2CA2CA9CA1CA12 | |
| SCHEMBL11089868 | 0.77 | ALDH1A1 (0.56) | CYP2C9KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11087332 | 0.77 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDHSD17B10SGK1 | |
| SCHEMBL11092954 | 0.76 | SGK1 (0.40) | PTGES2KDM4EALDH1A1HPGDHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL27806367 | 0.76 | SLC22A12 (0.48) | PTGES2CA2CA9CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033984-B1 | NEW SULPHONYL COMPOUNDS, METHOD OF PREPARING THE NEW COMPOUNDS, AS WELL AS APHICIDAL COMPOSITIONS ON THE BASIS OF THE NEW COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-06-06 | — | — | EP | disclosed |
| US-4379157-A | Sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1983-04-05 | — | — | US | disclosed |
| EP-0033984-A1 | New sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-08-19 | — | — | EP | disclosed |