Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085124 | 0.81 | PTGES2 (0.44) | KDM4EALDH1A1HPGDHSD17B10SGK1 | |
| SCHEMBL15461576 | 0.81 | EPAS1 (0.45) | KDM4EALDH1A1HPGDHSD17B10TAS1R3 | |
| SCHEMBL11087332 | 0.81 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDHSD17B10SLC22A12 | |
| SCHEMBL11092954 | 0.80 | SGK1 (0.40) | KDM4EALDH1A1HPGDHSD17B10SLC22A12 | |
| SCHEMBL7761256 | 0.79 | ALDH1A1 (0.44) | TRPV4ALDH1A1SLC22A12HTTPKM | |
| SCHEMBL2570257 | 0.79 | SLC22A12 (0.47) | TRPV4KDM4EALDH1A1SLC22A12TAS1R3 | |
| SCHEMBL4021944 | 0.78 | CA1 (0.39) | TRPV4ALDH1A1HSD17B10SLC22A12EPAS1 | |
| SCHEMBL4972108 | 0.78 | CYP1A2 (0.43) | TRPV4KDM4EALDH1A1HPGDSLC22A12 | |
| SCHEMBL11089868 | 0.77 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDHSD17B10SGK1 | |
| SCHEMBL11090525 | 0.75 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDHSD17B10SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140135215-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2014-05-15 | — | — | US | disclosed |
| US-8629284-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-14 | — | — | US | disclosed |
| US-8524896-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524896-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524896-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-20110218101-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-08 | — | — | US | disclosed |
| EP-2344464-A1 | 4-HALO-3 -AMINO- L, 2 -BENZISOTHIAZOLE COMPOUNDS AS PESTICIDES | Syngenta Participations AG (CH) | 2011-07-20 | — | — | EP | disclosed |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| EP-2265579-A2 | 2-CYANOBENZENSULFONAMIDE DERIVATIVES HAVING PESTICIDAL PROPERTIES | Syngenta Participations AG (CH) | 2010-12-29 | — | — | EP | disclosed |
| WO-2010054926-A1 | 4-HALO-3 -AMINO- L, 2 -BENZISOTHIAZOLE COMPOUNDS AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-05-20 | — | — | WO | disclosed |
| WO-2009109539-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-11 | — | — | WO | disclosed |
| EP-0033984-B1 | NEW SULPHONYL COMPOUNDS, METHOD OF PREPARING THE NEW COMPOUNDS, AS WELL AS APHICIDAL COMPOSITIONS ON THE BASIS OF THE NEW COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-06-06 | — | — | EP | disclosed |
| US-4379157-A | Sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1983-04-05 | — | — | US | disclosed |
| EP-0033984-A1 | New sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218101-A1 | CHEMICAL COMPOUNDS | CBR3, C3AR1, CCNY | TRPV4 3232/4885KDM4E 3536/4885ALDH1A1 2022/4885 |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | CBR3, CBR1, CYCS | TRPV4 2083/4885KDM4E 3169/4885ALDH1A1 3381/4885 |
| US-20140135215-A1 | CHEMICAL COMPOUNDS | CBR3, CCNY, C3AR1 | TRPV4 3101/4885KDM4E 3263/4885ALDH1A1 2199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.