Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089868 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HTTKAT6AKDM4EHSD17B10 | |
| SCHEMBL970204 | 0.81 | TRPV4 (0.42) | ALDH1A1HTTKAT6AKDM4EHSD17B10 | |
| SCHEMBL11083190 | 0.80 | HTT (0.46) | ALDH1A1HTTKDM4EHSD17B10HPGD | |
| SCHEMBL15461576 | 0.77 | EPAS1 (0.45) | ALDH1A1HTTKDM4EHSD17B10HPGD | |
| SCHEMBL11085124 | 0.77 | PTGES2 (0.44) | ALDH1A1KDM4EHSD17B10HPGDSGK1 | |
| SCHEMBL11087604 | 0.76 | RAB9A (0.41) | ALDH1A1HTTKAT6AKDM4EHSD17B10 | |
| SCHEMBL11092954 | 0.75 | SGK1 (0.40) | ALDH1A1KAT6AKDM4EHSD17B10HPGD | |
| SCHEMBL11087621 | 0.71 | KDM4E (0.34) | ALDH1A1KAT6AKDM4EHSD17B10HPGD | |
| SCHEMBL11090525 | 0.71 | ALDH1A1 (0.37) | ALDH1A1HTTKAT6AKDM4EHSD17B10 | |
| SCHEMBL186269 | 0.71 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10HPGDTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033984-B1 | NEW SULPHONYL COMPOUNDS, METHOD OF PREPARING THE NEW COMPOUNDS, AS WELL AS APHICIDAL COMPOSITIONS ON THE BASIS OF THE NEW COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-06-06 | — | — | EP | disclosed |
| US-4379157-A | Sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1983-04-05 | — | — | US | disclosed |
| EP-0033984-A1 | New sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-08-19 | — | — | EP | disclosed |